Somatic Cell Mutations in Atomic Bomb Survivors

Glaucoma in atomic bomb survivors.

Radiation has been associated with increases in noncancerous diseases. An effect of low-dose radiation on the prevalence of clinically detected glaucoma has not been previously reported. We therefore investigated the prevalence of glaucoma in A-bomb survivors and its possible association with radiation dose. A total of 1,589 people who participated in the clinical examination program for A-bomb...

Leukemia in Atomic Bomb Survivors

EUKEMOGENESIS induced by repeated exposures to x-ray and other forms of radiation energy has long been recognized in man and in experimental ammals.’3 The explosion of the atomic bombs in Japan exposed two large human populations to single brief but massive doses of ionizing irradiation and subsequently a marked increase in leukemia among survivors was reported.4 ‘ The present study consists of...

T-cell immunosenescence and inflammatory response in atomic bomb survivors.

In this paper we summarize the long-term effects of A-bomb radiation on the T-cell system and discuss the possible involvement of attenuated T-cell immunity in the disease development observed in A-bomb survivors. Our previous observations on such effects include impaired mitogen-dependent proliferation and IL-2 production, decreases in naive T-cell populations, and increased proportions of ane...

Leukemia in Hiroshima atomic bomb survivors.

A CAUSAL RELATION between radiation and leukemia has been well demonstrated.112 The reported cases of leukemia in people exposed to radium, 1.’I 4 1 occupational x-ray,’ I therapeutic x-ray to the thyroid region in childhood’92#{176} and possibly in utero diagnostic x-ray,2’ have been few in number. Estimates of the increased risk associated with exposure of man to radiation depend heavily upon...

Atomic bomb injuries among survivors in Hiroshima.